Center for Neurologic Disease
Brigham and Women's Hospital
Harvard Medical School
Kuchroo Publications 1990-1994
Kuchroo VK, Steele JK, O'Hara RM Jr., Jayaraman S, Selvaraj P, Greenfield E, Kubo RT, and Dorf ME. Relationships between antigen specific helper and inducer suppressor T cell hybridomas. J. Immunol. 1990; 145:438-48.
Collins M, Kuchroo VK, Whitters MJ, O'Hara RM Jr., Kelleher K, Kubo RT and Dorf ME. Expression of functional ab T cell receptor gene rearrangements in suppressor T cell hybridomas correlates with antigen binding, but not with suppressor cell function. J. Immunol. 1990; 145:2809-19.
Wilson SD, Kuchroo VK, Israel DL, and Dorf ME. Expression and characterization of TCA3: A murine inflammatory protein. J. Immunol. 1990; 145:2745-50.
Gallina MJ, Kuchroo VK, and Steele JK. Serologic, biologic and Western blot analysis of a T suppressor factor with specificity for the hapten 4-hydroxy-3-nitrophenyl acetyl derived from serum-free medium. J. Immunol. 1990; 145:3570-7.
Kuchroo VK, Billings PR, Levine C, Martin CA, Kubo RT and Dorf ME. Antigen specific and antibody mediated growth inhibition of suppressor T cell hybridomas. Roles of H-2 and the CD3-TcRa/b complex. J. Immunol. 1990;145:1059-65.
Kuchroo VK, Sobel RA, Yamamura T, Greenfield E, Dorf ME, Lees MB. Induction of experimental allergic encephalomyelitis by myelin proteilipid-protein-specific T cell clones and synthetic peptides. 1991; Pathobiology 59:305-12.
Kuchroo VK, Byrne MC, Atsumi Y, Greenfield E, Connoly JB, Whitters MJ, O'Hara RM Jr., Collins M, Dorf ME. T cell receptor a chain plays a critical role in antigen-specific suppressor cell function. Proc. Natl. Acad. Sci. USA. 1991; 88:8700-4.
Ozdermirli M, El-Khatib M, Bastiani L, Akdeniz H, Kuchroo VK, Ju S.-T. The cytotoxic process of CD4 Th1 clones. J. Immunol. 1992; 149:1889-95.
Sobel RA, and Kuchroo VK. The Immunopathology of Acute Allergic Encephalomyelitis induced with myelin Proteolipid Protein: T cell receptors in inflammatory lesions. J Immunol. 1992; 149:1444-51.
Greer JM, Kuchroo VK, Sobel RA, Lees MB. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. J Immunol. 1992; 149:783-8.
Kuchroo VK, Sobel RA, Laning JC, Martin CA, Greenfield E, Dorf ME, Lees MB. Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein: Fine specificity and TcR Vb usage. J Immunol. 1992; 148:3776-82.
Kuchroo VK, Martin CA, Greer JM, Ju S-T, Sobel RA, Dorf ME. Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein specific T cell clones to mediate experimental allergic encephalomyelitis. J. Immunol. 1992; 151:4371-82.
Kuchroo VK, Collins M, Al-Sabbagh A, Sobel RA, Whitters MJ, Zamvil SS, Dorf ME, Hafler DA, Seidman JG, Weiner HL, Rimm IJ. T cell receptor usage determines disease susceptibility in experimental autoimmune encephalomyelitis: studies with T cell receptor Vb 8.2 transgenic mice. J. Exp. Med. 1994; 179: 1659-64.
Franco A, Southwood S. Arrhenius T, Kuchroo VK, Sette A, Ishioka GY. T cell receptor antagonist peptides are highly effective inhibitors of Experimental Autoimmune Encephalomyelitis. Eur. J. Immunol. 1994; 24:940-6.
Zamvil SS, Al-Sabbagh A, Nelson P, Kaul D, St. Charles M, Mitchell DJ, Steinman L., Weiner HL, Kuchroo VK. "Lupus-prone" mice are susceptible to organ-specific autoimmune disease, experimental allergic encephalomyelitis. Pathobiology 1994; 62:113-9.
Kuchroo VK, Greer JM, Kaul D, Ishioka G, Franco A, Sette A, Sobel RA, Lees MB. A single TCR antagonist peptide inhibits Experimental Allergic Encephalomyelitis mediated by a diverse T cell repertoire. J. Immunol. 1994; 153:3326-36.
Chen Y, Kuchroo VK, Inobe J, Hafler DA, and Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994; 265:1237- 40.
